null Skip to main content

Weed Paranoia Cure: Can Black Pepper Really Help with THC-Induced Anxiety?

Weed Paranoia Cure: Can Black Pepper Really Help with THC-Induced Anxiety?

Posted by The Weed Warlock on Mar 21, 2023

Shop our store.

Jump over to our homepage and check out our selection of legal THC, CBD and other cannabis products.


If you've ever consumed a little too much cannabis and found yourself spiraling into a world of paranoia and anxiety, you're not alone. Many cannabis enthusiasts have searched for a quick and effective remedy to ease their discomfort. Some might be surprised to learn that the answer might be hiding in their kitchen cabinets – black pepper. In this blog post, we'll explore the claim that black pepper can reduce anxiety and paranoia from being too high on THC. For some that could be from marijuana or for super sensitive folks even the trace amounts found in cbd weed. We'll dive into the science behind it, discuss its connection to terpenes, and see if sneezing has any role to play. So, buckle up and let's take a trip down this spicy road!

Neil Young and Howard Stern: Endorsing Black Pepper for THC-Induced Anxiety

The idea that black pepper can help with THC-induced anxiety and paranoia first gained traction when legendary musician Neil Young mentioned it during an interview with Howard Stern. Young claimed that he would chew on a few black peppercorns when he felt too high, and it would help calm him down (1).

Later, comedian and podcast host Joe Rogan echoed Young's sentiments on his show, "The Joe Rogan Experience," further popularizing the idea that black pepper could be a weed paranoia cure (2). But are these claims based on scientific evidence, or are they just blowing smoke? Let's find out.

The Science Behind Black Pepper and THC

The connection between black pepper and THC might seem far-fetched at first, but there's actually some scientific basis for this claim. The secret lies in the terpenes – the organic compounds responsible for the unique aroma and flavors of plants, including black pepper.

Terpenes are believed to have various therapeutic effects, and their interaction with cannabinoids (like THC) in the body can influence the overall effects of cannabis. This phenomenon is known as the "entourage effect" (3). One particular terpene, beta-caryophyllene (BCP), is found in both black pepper and cannabis. BCP has been shown to possess anti-inflammatory, analgesic, and anxiolytic (anxiety-reducing) properties (4).

BCP is unique among terpenes because it can directly interact with the body's endocannabinoid system, specifically binding to the CB2 receptors (5). These receptors are primarily found in the immune system and are known to modulate pain and inflammation. Importantly, CB2 receptors don't produce the psychoactive effects associated with THC, which bind to the CB1 receptors in the brain.

By binding to the CB2 receptors, BCP is thought to help counteract some of the anxiety and paranoia-inducing effects of THC, which primarily acts on CB1 receptors. However, it's important to note that the scientific evidence supporting this claim is still limited, and more research is needed to fully understand the interaction between black pepper and THC.

Black Pepper, Sneezing, and Anxiety

Some might wonder if the simple act of sneezing, which can be triggered by inhaling black pepper, could help alleviate THC-induced anxiety and paranoia. Sneezing is a natural reflex that helps clear irritants from the nasal passages. While it might provide a temporary distraction from the uncomfortable sensations of being too high, there's no evidence to suggest that sneezing itself can reduce anxiety or paranoia related to THC consumption.

That being said, if you're ever feeling overwhelmed by THC-induced anxiety, focusing on your breathing and taking slow, deep breaths can help. This might not be directly related to black pepper or sneezing, but it's a proven technique for reducing anxiety in general.

So, Does Black Pepper Work as a Weed Paranoia Cure?

Although the idea that black pepper can help with THC-induced anxiety and paranoia is intriguing and supported by some scientific evidence, it's essential to approach this potential remedy with caution. The research on the interaction between terpenes like BCP and THC is still in its early stages, and everyone's individual response to cannabis and black pepper might differ.

If you're interested in trying black pepper as a weed paranoia cure, it's important to remember that moderation is key. Chewing on a few peppercorns or taking a whiff of freshly ground black pepper might provide some relief, but it's unlikely to be a magic bullet for everyone.


In conclusion, while there is some scientific evidence pointing to the potential benefits of black pepper in alleviating THC-induced anxiety and paranoia, it's important to remember that everyone's experience may vary. As research on terpenes and their interaction with cannabinoids continues to grow, we might gain a better understanding of how black pepper and other natural remedies can help with cannabis-related anxiety. Until then, if you're ever feeling too high, remember to take deep breaths, stay calm, and maybe give black pepper a try – but don't expect it to be a one-size-fits-all solution.


  1. Rolling Stone. (2014). Neil Young Talks 'Strange' New Album, 'Pono' Music Service and More. Retrieved from
  1. The Joe Rogan Experience. (Various episodes). Retrieved from
  2. Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344-1364.
  3. Gertsch, J., Leonti, M., Raduner, S., Racz, I., Chen, J. Z., Xie, X. Q., ... & Karsak, M. (2008). Beta-caryophyllene is a dietary cannabinoid. Proceedings of the National Academy of Sciences, 105(26), 9099-9104.
  4. Bento, A. F., Marcon, R., Dutra, R. C., Claudino, R. F., Cola, M., Leite, D. F., & Calixto, J. B. (2011). β-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPARγ pathway. The American journal of pathology, 178(3), 1153-1166.

Popular Products

Check out these customer favorites.